Stem Cells (CD34+) and Functional Recovery Post-Stroke (Initial Work)

14 Aug


A recent study by a group from NHS Imperial College Healthcare in London has found a possible treatment for acute ischemic stroke using a patient’s own stem cells.

The use of stem cells, specifically CD34+ hematopoietic cells, has been shown to promote neurogenisis and angiogenesis, thereby improving functional recovery after stroke in non human models but this represents the first trial of its kind in humans.

The CD34+ cells were harvested from the bone marrow of five acute severe stroke patients. The cells were then infused into the carotid artery of these patients within seven days of stroke onset. The initial reasoning for the study was to test tolerance and safety of the procedure however, a significant side benefit was noted. All patients showed improvements on clinical tests over the six month follow up period, with three of five being independent in ADLs.

Interestingly, authors do not seem to suggest…

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